Policy Issues Paper free essay sample

Violence in any form can have a lasting effect on a person. Children who witness violence are permanently scarred because of what they are seeing. Children who witness family or domestic violence are affected in ways similar to children who are physically abused. Children are often unable to establish nurturing bonds with either parent and are at a greater risk for abuse and neglect if he or she lives in a violent home. Statistics show that an estimated 3. 3 million children are exposed to violence against their mothers or female caretakers by family members in their home each year (Ackerman Pickering, 1989). When a spouse, woman or male is abused, and there are children at home, the children will be affected by the abuse. This paper will refer to the video, â€Å"Child Exposure to Domestic Violence. † â€Å"Child Exposure to Domestic Violence† is a video about personal crime that looks at how children react to witnessing domestic violence. We will write a custom essay sample on Policy Issues Paper or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page The children in the video have witnessed their father physically abusing their mother and have heard his or her father making death threats toward his or her mother. The video starts off referring to the children of O.  J. and Nicole Brown-Simpson. Nicole was a victim of domestic violence and was found murdered with her boyfriend. O. J. was found not guilty of her murder but was found guilty in her civil lawsuit. The video asks what the children saw or heard, if anything. Studies show that child abuse occurs in nearly 30 to 60% of family violence cases that involve families with children. 6,000 American families were surveyed, and it was found that 50% of men who assault their wives, also abuse his children. Research shows that 80 to 90% of children living in homes where there is domestic violence are aware of the violence (American Psychological Association, Violence and the Family: Report of the APA Presidential Task Force on Violence and the Family, 1996). The causal factors addressed in the video were of a man who went to his ex-girlfriend’s residence and attempted to break in by climbing into a window. Out of fear she contacted police and had him arrested for violating the order of protection she had placed on him. In the video, the three year-old son was standing in the doorway and witnessed his father getting arrested. The little boy time and time again has witnessed his parents arguing and fighting. The police have been to their house more than 20 times and his father served six months in jail for domestic violence. Children react to their environment in different ways, and those reactions can vary, depending on the childs gender and age. Children exposed to family violence are more likely to develop behavioral, emotional, psychological, and social problems than those who are not. Recent research indicates that children who witness domestic violence show anger and temperament problems, depression, low self-esteem, and more anxiety than children who do not witness violence in the home. The trauma they experience can show up in behavioral, physical, social, and emotional disturbances that affect their development and can continue into adulthood. No financial issues were discussed in the video. However, the financial issues that can be associated are a loss of a two person income in the family. When one family member goes away who may be the primary breadwinner of the family, the household becomes the responsibility of the mother which in-turn can cause a financial strain. Another financial issue can be legal fees and court costs. The father served six months in jail for domestic violence and was led away in handcuffs for violating the restraining order. He will have to obtain a lawyer and pay restitution to the court or his ex-girlfriend. The father also can be responsible for child support and may lose his employment because of his legal troubles. The basis for this selected video was as a result of having the experience a child who was raised in household that witnessed my father abusing my mother. Also witnessed my siblings experiencing the same type of abuse from their significant others. Was not raised in a two parent household, was raised only by my mother who struggled to heal from her scars of being abused for many years. I can relate to the video by knowing what the children were feeling at the time, the fear, shock, and hurt that I witnessed growing up. From the criminal aspect, this video shows the Actus Reus, the criminal act of being caught at the scene attempting to gain entry into his ex-girlfriends residence. Domestic violence is represented by a negative reaction. Men hit and abuse other family members because of control and because they have feelings of shame and humiliation which leads to feelings of anger, hostility and rage. Pathological or emotional conflict in the forms of aggression and violence occur, whether an individual has unacknowledged humiliation, dissociation, or depression and is transformed into reactive rage and anger.

Free Online Public Schools for Florida Students K-12

Free Online Public Schools for Florida Students K-12 Florida offers resident students the opportunity to take online public school courses for free. Below is a list of no-cost online schools currently serving elementary and high school students in Florida. In order to qualify for the list, schools must meet the following qualifications: classes must be available completely online, they must offer services to state residents, and they must be funded by the government. Virtual schools listed may be charter schools, state-wide public programs, or private programs that receive government funding. List of Florida Online Charter Schools and Online Public Schools Florida Connections AcademyFlorida Virtual School Florida Cyber Charter Academy About Online Charter Schools and Online Public Schools Many states now offer tuition-free online schools for resident students under a certain age (often 21). Most virtual schools are charter schools; they receive government funding and are run by a private organization. Online charter schools are subject to fewer restrictions than traditional schools. However, they are reviewed regularly and must continue to meet state standards. Some states also offer their own online public schools. These virtual programs generally operate from a state office or a school district. State-wide public school programs vary. Some online public schools offer a limited number of remedial or advanced courses not available in brick-and-mortar public school campuses. Others offer full online diploma programs. A few states choose to fund â€Å"seats† for students in private online schools. The number of available seats may be limited and students are usually asked to apply through their public school guidance counselor. Choosing a Florida Online Public School When choosing an online public school, look for an established program that is regionally accredited and has a track record of success. Be wary of new schools that are disorganized, are unaccredited, or have been the subject of public scrutiny. For more suggestions on evaluating virtual schools see how to choose an online high school.

What kind of coping mechanisms employees use under pressure at their Essay

What kind of coping mechanisms employees use under pressure at their job - Essay Example Slovik (2009) said that no one lives without experiencing stress. A study conducted revealed that 70 to 90 percent of the respondents experience stress at the workplace (Stress 2007). It cannot be eliminated since the workers are human beings who are affected by social and environmental factors. An individual might misinterpret another’s action causing emotional stress. It may come from a superior, the customer or even from a subordinate who does not perform according to the corporate standards. Domestic and personal problems can be brought at the workplace that make the worker easily susceptible to stress. Even the physical environment can be a source of stress. Extreme stress, however, is detrimental upon the body, personal relationship and happy life (Slowik 2009). Thus, with the inevitability of stress, the organization has to devise means to meet the problems of stress at the workplace. Even the most efficient worker under stress will perform unsatisfactorily. Poor performance will affect productivity and profitability of the company. Indeed, stress is a serious matter in any organization to take into consideration in its rules and policies. The company has to formulate policies and create a unit that would handle and manage workplace stress and stress-related scenarios. The organisation must also engage a professional with expertise on the subject that would train and inculcate upon the managerial staff on the proper way to manage stress among employees in order not to disrupt the company production and work flow. Stress can result from the demand of the tasks, the demand of the role and the structure of the organization (Khan, Raza, & Ali 2007). It refers to a person’s response to â€Å"stressors in the environment (Khan et al. 2007, p. 2). Selye (1976, cited in Khan et al. 2007) referred to it in the General Adaptation Theory as a response involving biological and physiological aspects. It also refers to

The Travels of a T-Shirt - Government Subsidies Essay

The Travels of a T-Shirt - Government Subsidies - Essay Example In agreement with government subsidies, this form of government intervention reduces the cost of production and encourages the producers to increase output. Government intervention/producer subsidies are of various forms. An example is state subsidies. State subsidies are financed from general taxation or by borrowing (Schuster, 2006). Government subsidies cause various productive firm’s supply curve to shift to the right. The amount spent on subsidy by the government is equivalent to the subsidy per unit multiplied by total output (Day & Schoemaker, 2005). A direct subsidy commonly offered by a government to supplement consumer’s demands has the effect of boosting demand. This results in an outward shift of demand. Examples of subsidies include an input subsidy, bails, fiscal assistance (loans and grants), government grants to cover losses made by business and a guaranteed on the factor cost of a product. Subsidies make sense in various demand and supply situations of the economy. The travels of T-shirt in Global Economy represents some of the scenarios in which subsidies may play a crucial role in the examination of market forces, power and politics of world trade (Rivoli, 2015). The overall international trade topic is a very crucial topic to discuss in the abstract though when this topic is focused on a single product, it is easy to be dealt with (World Bank Group, 2011). Subsidies in the international trade in most cases dwell with specific products. Only in extreme cases in the world economy do subsidies deal with conglomerate products. Through the story of travels of T-shirt, globalization advocacy is portrayed critically as the major issue behind international trade and individual country’s economy development (Prono, 2006). The competitive economic markets and increased living standards at the expense of the maximum and minimum wage bills among different

The role that agents of socialization play in shaping an individuals Essay

The role that agents of socialization play in shaping an individuals political culture - Essay Example In fact, journalism has the capability to challenge the political arrogance displays and acts as a potential channel to display the voices of political situations in a particular region. The news media conveys messages, meanings and symbols to the wider society and political news can actually affect the image of a politician or a political party in general (Schudson, 2002). Education system also has a role in forming the political culture of an individual. People learn through the various books, theories and history the political culture and heritage enjoyed in the country. Also civics and law gives a lot of insight about the political structures and systems prevalent and the constitutional rights enjoyed by a particular nation thereby helping an individual to form an opinion (Zechenter, 1997). Other than these, religion and the workplace of an individual are important components shaping the political culture of an individual. Religion is especially a dominant force in forming political culture. Also the workplace of an individual helps him to get information and form opinions about political culture. If the individual meets people from different regions coming from varied cultures, values, beliefs and religions then he may have more knowledge about the cultures and opinions of other individuals. However, according to me the education systems and the media portrayal of the issues taking place have helped in forming a political culture. The history and civics subject helps us to know more about the political systems in the country and the media including newspaper, television and radio have helped in forming my personal opinion about the political culture. Another important factor which helped to shape my political culture is my parents, peers and relatives. Discussions and debates help in knowing more information thereby helping in forming an opinion about the political culture. To conclude, a culmination of

Effects of Language on a Specific Region

Effects of Language on a Specific Region Crystal Mullen ASSIGNMENT: Select a specific region that interests you, such as South America, Central America, Asia, etc., and research, as well as evaluate, the power of language in creating the idea of a region. Is language a self-sufficient and complete geographical model? Write a 1-2 page paper explaining your findings. Please be sure to substantiate your opinions with examples, as well as cite your resources using APA format. in length. Professor Sandve’s Explanation: 1) Define a region. What is a region? 2) Evaluate the power of language. Can you define a regions society, traditions, norms, climate, topography, etc. by evaluating the language? 3) Is language a self-sufficient and complete geographical model? What is a geographical model? If language is the only characteristic youre evaluating, can you fully define the region? I believe a region means something different to different people or industries. Before taking this class, I thought a region was that part of the basement or that portion of an attic that scary movies warned us to avoid. The Merriam-Webster dictionary had a different view: â€Å"Region: a part of a country, of the world, etc., that is different or separate from other parts in some way (Merriam-Webster.com, 2014)† This definition appears to speak more to the topic of geography because we are now discussing spatial locations that offer distinct characteristics that are found in that found in that location. However, I need to know what a region is from a geographer’s point of view. â€Å"Region: in geography, an area of the earth that displays distinctive grouping of physical or cultural phenomena or is functionally united as a single organizational unit (Getis, Bjelland, Getis, 2014).† This definition best describes geography in the for this assignment because it encourages me to pick an area of the world that I find interesting because of how various physical or cultural features are joined into one spatial location. One region that I that does interest me is Africa. Africa is the second largest continent in the world; as well as the world’s second most-populous continent. Within its borders one will find 54 countries that are share the home for the continent’s many mountains, rivers, valleys and deserts. First of all, the Atlas Mountains run from the southwestern portion of Morocco along the coastline of the Mediterranean, all the way to Tunisia’s eastern edge. Also, the Great Rift Valley is the continent’s ground form of depression. Here is found a series of geological faults at are approximately 4,000 miles in length. The extent of the Great Rift Valley extends from the Red Sea region near Jordan, to the country of Mozambique. Furthermore, Africa is home to the Congo River Basin which dominates the landscape of central Africa’s Democratic Republic of the Congo. Finally though certainly not I would be remiss to speak of Africa without speaking of the Sahara Desert. The Sahara Desert cover close those a third o f Africa’s surface. It is the world’s largest desert in the world at approximately 3,500,000 square miles in total size (World Atlas, 2014). Based on this the geographical information, I would be surprised to learn if there is a cohesion of language within the continent to unify the continent of Africa. The range of traditions and customs in Africa are as diverse as Africa’s geography. For example, when it comes to meal time, the men eat before the women. Children remain silent while adult meal conversation is in progress. Also, hospitality is very important to the country of Africa. When they welcome their guests, they wash their hands, clap, and offer their best meats as a symbol of graciousness. Furthermore, when it comes to courtship, it appears that it is the girl who initiates the process. She will send a multi-colored beaded bracelet to the boy of her choice. Each bead represents a secret meaning and once the courtship process is over the secret behind the beads are revealed. Finally, though certainly exhaustively, it is customary during an African wedding that the bride wears a wedding dress that reflects her culture’s traditions and heritage. Also, the bride and groom are often tied at the wrists with either cloth or braided grass as a symbol of their newly cr eated union (Drake, 2014). When I read these customs, I feel as if it is possible for language to be a complete self-sufficient model of its people because their customs appear to transcend their multi-faceted geography, The aspect about Africa is their massive diversity of languages and dialects. While no one appears to know for absolute certainty, the best estimate of the number of languages and dialects spoken in Africa are around 2,000. One group of African languages are known as the Afro-Asiatic language group of languages. The 400 languages under this umbrella is generally heard spoken in North, East, and Southwest Africa. Some examples of these languages include Aramaic, Amharic, Arabic, Hausa, Hebrew, and Tigrinya. Another family of languages heard spoken in Africa is the Khoisan, or language. This happens a language that may be dying out, it is currently spoken in Angola, Botswana, and Namibia. This is the family of fifty different languages that use mainly clicking or tonal sounds to communicate. Finally though certainly not exhaustively the language family that holds the greatest number of languages is the Niger-Congo language family. Under this umbrella of languages one will find almost 4 00 languages that are spoken by over 500 million people. Common languages that fall within this family include Igbo, Swahili, Yoruba, and Zulu (wiseGEEK, 2014). I find it fascinating that there are countless languages for a person in Africa to express the frustration of the desert sand, being insulted by a dinner guest or vowing his or her life to a new spouse. I find myself conflicted when I consider if language is a complete, self-sufficient geographical model of the region of Africa. On the one hand, because there are over 2,000 languages, spoken in Africa, I would say that each language and dialect is a perfect representation of the country, or portion of that country within Africa. If language were my only representation I was evaluating, I could easily define that particular region. On the other hand, because there are over 2,000 languages, spoken in Africa, I would say that each language and dialect creates the perfect storm for confusion for Africa as a whole. I don’t see how I could identify Africa as a continent because the continent cannot unite behind one or two languages. In this scenario, if language were my only representation I was evaluating, I would greatly struggle to define the continent because millions of African citizens would not be representing in my definition. Therefore, I find that the African languages bo th reflect and confuses the geographic model found in the continent of Africa. References Drake, F. (2014). African Customs. Retrieved January 26, 2014, from eHow.com: http://www.ehow.com/info_8582146_african-customs.html Getis, A., Bjelland, M., Getis, V. (2014, January 7). Glossary. In A. Getis, M. Bjelland, V. Getis, Introduction to Geography (pp. G-9). New York: McGraw Hill. Retrieved from Balanced Politics: http://www.balancedpolitics.org/affirmative_action.htm Merriam-Webster.com. (2014). Definiton of Region. Retrieved January 26, 2014, from Merriam-Webster.com: http://www.merriam-webster.com/dictionary/region wiseGEEK. (2014). How Many Languages are Spoken in Africa? Retrieved January 26, 2014, from wiseGEEK: http://www.wisegeek.org/how-many-languages-are-spoken-in-africa.htm World Atlas. (2014). Africa Map. Retrieved January 26, 2014, from World Atlas: http://www.worldatlas.com/webimage/countrys/af.htm World Atlas. (2014). Geography Africa. Retrieved January 26, 2014, from World Atlas: http://www.worldatlas.com/webimage/countrys/afland.htm

Truman Capotes In Cold Blood :: In Cold Blood Essays

Capote, Truman. In Cold Blood. New York: Random House, 1965. 343 pages. Summary. In Cold Blood is the true story of a multiple murder that rocked the small town of Holcomb, Kansas and neighboring communities in 1959. It begins by introducing the reader to an ideal, all-American family, the Clutters -- Herb (the father), Bonnie (the mother), Nancy (the teenage daughter), and Kenyon (the teenage son). The Clutters were prominent members of their community who gained admiration and respect for their neighborly demeanors. After being introduced to the Clutter family, the reader becomes acquainted with Dick Hickock and Perry Smith. The two were former inmates who met in prison. After their release, the men meet up for what Dick calls Aa perfect score.@ As it turns out, Dick=s cell mate had worked for the Clutters some years earlier and suggested to Dick that he check into employment at the Clutters= farm because the Clutters were such friendly, kindhearted people. The more Dick learned about the Clutters, the more he considered seeking fast cash as opposed to employment. During the trial in the last chapter of the book, however, Dick admitted that his sexual interest in teenage girls was the most powerful force in his decision to invade the Clutters= home. (Perry stopped him from harming Nancy.) Finally, the killers were identified by Dick=s former cell mate and tracked down in Las Vegas. In the time leading up to their arrest, the reader is offered greater insight into the characters of the two men. Because Perry opposed Dick=s crude behavior and showed compassion for the people Dick intended to harm or slight, we are left to feel a bit of sympathy for him. It becomes tempting to see Dick as the manipulative leader and Perry as the helpless follower. After the suspects were taken into custody, Perry eventually confessed that he had killed Herb, Bonnie, Nancy, and Kenyon -- tied each of them up, made sure they were comfortable, then shot each of them in the head with a shotgun. In addition, it was Perry who cut Herb=s throat. Though Dick didn=t actually pull the trigger or hold the knife, he shined the flashlight into the faces of the victims as Perry killed them. Both men were found guilty of 4 counts of premeditated murder, and each was sentenced to death. While awaiting their executions, they appealed several times, losing each time, but managing to have their execution dates postponed.

Speech to the new intake informing them of our expectations: The SS

am here today to tell you about Germanys greatest people, The SS. The SS belongs to Germany and every single one of you here should be very proud to be part of it. The SS is very important. It is led by extremely powerful leaders and if you are in the SS you have to be determined. There is no time for fun and games. Most of you in here are the Arian race (blond hair, blue eyes, tall and thin) which is what we want in Germany although if you are not, there is no need to worry because we have investigated your back round and you have no Jewish connections. I am going to start off today by talking about the appearance of the SS. The kinds of people we look for in the SS are no normal people. We are looking for amazingly fit human beings. People that are strong minded and people who could go through any think. The idea for the SS is blond hair, blue eyes, tall and thin. Although as I have already mentioned if you do not exactly fit into this category do not worry. One thing is certain though; we do not want any Jewish blood in you people. Jews are the people trying to destroy Germany so we need to stop them. I am now going to briefly talk to you about Germany glorious history from 1925. The SS was created in 1925. Its full name is the ‘Schutzstaffel', which means protection squad. We created the SS to provide protection for Hitler and other Nazi leaders. In the mid twenties the SS was not very important, it only had a few hundred members and was run by SA. When the SS got a new leader in 1929 things changed. Heninrich Himmer was the new leader, he cam from a well-off middle class family. He joined Nazis in 1923 after service in Army and Free Corps. In the 1929 he was 29 years old. Himmer was very ambitious when he took over the SS. In 1930 the SS and SA was separated. The SS continued to provide Hitler with protection. They were also given black uniforms to show their independence. They looked out for people being disloyal to Hitler. As this time went on the SS started to grow and carry out more functions. In 1932 the SS began to develop army-style units. When Nazis came to power in 1933 Himmler set out to bring all of German's police forces under SS control. There was some completion, which was getting in Himmlers way though. Opposition was not good and we had to get rid of it. For example Gustav von Kahr who betrayed Hitler in the Putsch in 1923 was murdered. Another murder squad went to the house of General Kurt Schliecher, a former chancellor, who had said things against Hitler. He was shot dead along with his wife. The most extensive and successful slaughter we had was the night of the long knives (30th June/1st July 1934). Many were killed on this night including several storm troopers. The leader Ernst Rohm was also killed. Another 400 were killed. This may seem like we took it to far but the Storm troopers were mostly thugs and greedy. They dreamed of seizing the money, businesses and properly of wealthy Germans and the land of the aristocratic Junker class. I am now going to move on to tell you about our main departments. We have many departments amongst us. Ill start off by telling you about the Gestapo. Hermann Georing controls the Gestapo. He was head of the big state of Prussia. The Gestapo was a secret police force. The Gestapo was established on April 26, 1933, in Prussia, from the existing organization of the Prussian Secret Police. The Gestapo was first simply a branch of the Prussian Police. The role of the Gestapo was to investigate and combat â€Å"all tendencies dangerous to the State.† It had the authority to investigate treason, espionage and sabotage cases, and cases of criminal attacks on the Nazi Party and on Germany. Another department is the ‘Death's Heads Units' which were set up to guard camps. These units treated prisoners in a barbaric fasion. Speical SS units called ‘Einsatzgruppen' were set up to deal with the resistance to Nazi rule in German-occupied counties. They deal with anyone who looks like a threat. Mostly the worst people like priests, polictal leaders and Jews are killed. The Waffen SS gew out of Hitler's SS bodygurad. The amount of people rose to half a million. The Waffen SS fough alonside ordinary Germans. It had a reputaion for being ruthless and burtal. I am now going to tell you about the aims of concentration camps. Concentration Camps were set up in Germany by Hermann Goering and Heinrich Himmler in 1933. The aim of these camps were to get rid of people who were ruining Germany and doing no good to the country. Most prisionors are Christains, Gypsies, homosexuals and Jews. These camps are good and teach people abit of law and order. If people disabay the rules of the camps there are consequences. The camps were a final solution I am going to finish off by telling you about role models. Reinhard Heydrich and myself should be role models. Reinhard Heydrich was a former naval officer who joined the SS in 1932, after his dismissal from the navy. He headed the SS Security Service, a Nazi party intelligence agency. In 1933-1934, he became head of the political police. You should look up to this man. I am the leader of this training school I so I expect respect from everyone here and then we will get on fine. I hope this speech has helped you understand a bit more than you originally knew about the SS.

Critical Analysis of Mass Spectrometry The WritePass Journal

Critical Analysis of Mass Spectrometry Introduction Critical Analysis of Mass Spectrometry Introduction1. Background:2. Methods of Ionization:3. Mass Analysers:4. The Mass Spectra:5. Mass Spectrometry in Synergy with other Techniques:6. Advances in Mass Spectrometry Instruments and their Limitations:7. The Future of Mass Spectrometry:References:Related Introduction 1. Background: The analytical technique that I have chosen to give an in-depth analysis of is Mass Spectrometry (MS) This analytical technique is basically the study of ionised molecules in the gaseous phase; its main use is in the determination of the molecular weight of the molecule in the sample under investigation by accelerating ions in a vacuum environment. While this analytical technique has been around for over one hundred years there are significant advances being made to this technique in order to cater for more adverse samples which will be discussed in more detail later on. The main difference between mass spectrometry and other spectroscopy methods such as NMR is that it not dependant on transitions between energy states which may be responsible for its popularity. The diagram shown below (Figure 1.1.) [1] shows a simple diagram of a common mass spectrometer using electron ionization:    Figure 1.1 represents a schematic diagram of an electron ionization-mass spectrometer showing the various processes involved. Courtesy of www.molecularstation.com. In its simplest form the process of determining the molecular weight of the sample typically occur over four main stages which are: Sample volatilisation, Ionisation, Separation and detection. Sample volatilisation: The sample to be analysed if gaseous or volatile can be readily inserted into the mass spectrometer with the more solid samples requiring heating before insertation in order to construct a more volatile or gaseous sample. As can be seen form the above figure the sample is then moved further down the spectrometer towards the area where ionization of the molecules occurs.   Ionization: The sample is then hit with a barrage of high energy electrons from an electron gun with a charge of around 70 electron volts (eV). When the molecules collide with the high energy electron beam energy is transferred from the beam to the molecules which cause an acceleration of the molecules. These molecules may then dump an electron forming cation known as the molecular ion (M+) [2]. This interchange is represented in the equation below (Figure 1.2.): M  Ã‚  Ã‚  Ã‚  Ã‚   +  Ã‚  Ã‚  Ã‚   e  Ã‚     Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   M+  Ã‚  Ã‚   +  Ã‚  Ã‚   2e   Moleccular Ion This electron barrage usually results in most of the molecular ions fragmenting causing some of the fragments to not gain any charge and remain neutral and have no further part to play. The main purpose of ionisation is to donate a charge to the sample in order for the molecules to break up and become charged. The ionization method discussed here is electron ionisation however there are many other more methods of ionization which will be discussed in detail later on in my analysis. Separation: This beam of newly charged molecular ions then proceed through a mass analyzer which in this case is a very strong controllable magnetic field which separates the charged molecules according to their mass to charge ratio (m/z) causing some of the molecules which are â€Å"too heavy† or â€Å"too light† to be thrown towards the top or bottom of the spectrometer and hence avoid detection. By varying the magnetic field, ions with different m/z values can be detected. Just like there are many different ionization methods for different applications there are also several types of mass analyzers which will also be discussed later. A fundamental consideration in mass spectrometry at this point is mass resolution, defined as R = M/∆M. where R is the resolution, M is the mass of particle and ∆M is the mass difference compared to adjacent peak with overlap at 10% of peak height. Nowadays a magnetic sector analyzer can have R values of 2000-7000 depending on the instrument [3]. Detection: the final stage in the process is comprised of a detector which then amplifies and records the mass of the ions according to their m/z values. The detector may be set up for detection of molecular ions possessing different mass to charge ratios. The Molecular ions each have a mass that is almost identical to the mass of the molecule (M) and due to the fact that the charges on most of the molecules are usually 1, the value of m/z obtained for each of the ions is simply its mass. The data collected by the detector is fed to a recorder and is presented in the form of a plot of the numbers of ions versus their m/z values [3]. An example of this type of plot is shown below in figure 1.3. [4]: Figure 1.3: A typical graph produced for a sample using mass spectrometry. Picture courtesy of www.research.uky.edu. 2. Methods of Ionization: Electron Ionization (EI): as described above is the simplest method for converting the sample to ions and this method is found on the most common mass spectrometers. Many other simple and complex ionization methods exist for analyzing various samples. Some of these methods include: Chemical Ionization (CI): This is a softer ionization method than EI, causing less fragmentation of the sample under investigation and hence it is mainly used for more sensitive compounds such as 2, 2-dimethylpropane for example which is prone to fragment with little stress. This decrease in fragmentation is due to the ions arising from a chemical reaction rather than bombardment and hence possesses less energy than those produced from EI. In Chemical ionization the molecules to be studied are mixed with an ionized carrier gas which is present in excess. Common carrier gases for CI include ammonia, methane, isobutene and methanol. The selection of the carrier gas depends on the degree of ion fragmentation required. Different carrier gases produce different mass spectra plots. The main advantage of CI is its softer approach lending to clearer results over EI for some samples. Other advantages include the relatively cheap and strong hardware as with EI. The main drawback of using chemi cal ionization in mass spectrometry is the fact that like electron ionization the sample must be readily vaporised in order for the molecules to gain that vital charge. This immediately dismisses the use of high molecular weight compounds and biomolecules [3]. It’s obvious therefore that CI and EI are very similar methods of ionization and due to this many of the modern day mass spectrometers can switch between these two methods effortlessly. Electrospray Ionization (ESI): is a type of atmospheric pressure ionization. This technique is very useful for studying the high biomolecular weight molecules and other samples which may not be very volatile as discussed above. The sample to be investigated is sprayed through a fine capillary which has a charge on its surface, the sample then enters the ionization chamber resulting in the production of multiple charged ions along with single charged ions. This formation of multiple charged ions is very useful in the mass spectrometry analysis of proteins [3]. It is important to note that negative ions may also be formed in ESI and the operation may need to be reversed. ESI has become much more common over the last few years as it relies on a sample in solution which permits its use in LC-MS [5]. Thermospray Ionization (TSI) is closely related to ESI differing only in the fact that it relies on a heated capillary rather than a charged capillary; however ESI remains the more popular of the two methods. Atmospheric-pressure chemical Ionization (APCI): It is obvious form the title that APCI is also a form of atmospheric pressure ionization resulting in a similar interface being used for both methods. This method was born in the 1970’s when it was first combined with liquid chromatography (LC) by Horning et al [6] who conveyed a new atmospheric ion source which used 63Ni beta emission in order to produce the required ions. Even tough APCI and ESI are harmonizing methods the main advantage APCI has over ESI is that it is more effective at determining the mass spectra for less polar compounds due to the reality that the gas phase ionization is more effective in APCI. Many MS instruments are now readily available with high mass resolution and accurate mass measurement, properties which are not as readily available with GC-MS instruments. Fast Atom Bombardment (FAB): this type of ionization method is primarily used for large polar molecules. The sample to be studied is usually dissolved in a liquid matrix which is non-volatile and polar such as glycerol. This sample is then bombarded with a fast atom beam such as Xe atoms which picks up electrons thus causing ionization from this reaction. This is a simple and fast method to use and is very good for high-resolution measurements. On the downside however it may be hard to compare low molecular weight compounds from the chemical back ground which is always high [5]. Desorption Chemical Ionization (DCI), Negative-ion chemical ionization (NCI), Field Ionization (FI) and Ion Evaporation are other less common ionization methods used in mass spectrometry. 3. Mass Analysers: As described earlier the mass analyzers are used to separate the various ions according to their mass to charge ratio (m/z) and hence focus the ions with the desirable m/z value towards the detector. Some of the mass analyzers available include; Double-Focusing Mass Analyzers, Quadrupole Mass Analyzers, Time-of-Flight Mass Analyzers and Ion Trap Mass Analyzers. Double-Focusing Mass Analyzers are used when a high resolution is of paramount importance. This high resolution is achieved by modifying the basic magnetic design. The beam of ions passes through an electrostatic analyser before or after the magnetic field causing the particles to travel at the same velocity resulting in the resolution of the mass analyzer increasing dramatically. Resolution may be varied by using narrower slits before the detector. It is important to note that this type of analyzer reduces sensitivity but increases accuracy resulting in a fine line between success and failure with regards to detection, for this reason this type of mass analyzer is only used for very selective purposes. Quadrupole Mass Analyzers do not make use of magnetic forces for mass detection; instead they are composed of four solid rods arranged parallel to the direction of the ion beam. Using a combination of direct-current and radiofrequency the quadrupole separates the various ions according to their mass extremely quickly. Quadrupole mass analyzers are most on most GC-MS instruments. Time-of-Flight Mass Analyzers (TOF) operate by measuring the time taken for an ion which has been produced to travel for the ion source to the detector [7]. This is based on the simple assumption that the lighter ions will have a greater velocity and thus will strike the detector first. This type of analyzer has become more and more common in recent years due to the fact that the electronics used in this analyzer have become much more affordable since it was first introduced in the 1940’s. In recent years the resolution and sensitivity of TOF have been increased by the insertation of a reflective plate within the flight tube itself [8]. The main area that this type of analyzer is used is in Matrix Assisted Laser Desorption Mass Spectrometry (MALDI-MS) discussed later. The Ion Trap Mass Analyzer is composed of two hyperbolic end cap electrodes and a doughnut shaped ring electrode [7]. It is very similar to the quadrupole analyzer in resolution terms and basics however the ion trap is more sensitive. 4. The Mass Spectra: The main interest that anybody has from the mass spectra is the molecular weight of the sample that was processed. The value of m/z at which the molecular ion (M+) appears on the mass spectrum tell us the molecular weight of the original molecule. The most saturated ion formed from the ionization provides us with the tallest peak in the spectra know as the base peak (Figure 1.2). From this information the determination of very exact molecular weights of substances may be deduced which is probably the most important application of mass spectrometers. This determination also allows use to distinguish between different substances with a very similar molecular mass which we are unable to do ourselves. For example; the molecule C14H14 has a molecular mass of 182.1096 and the molecule C12H10N2 has a molecular mass of 182.0844. These two molecules may only be differentiated by MS as there is only 0.0252 in the difference even tough they are two completely different molecules. The type of MS instrument used in this case is a Double Focusing Mass Spectrometer as discussed briefly above which is capable of providing measurements accurate to 0.0001 atomic mass units. The chance of two compounds having the exact same mass spectra is very unlikely and therefore it is possible to identify an unknown compound by comparing its mass spectra obtained with that of a known library of mass spectra for various compounds. 5. Mass Spectrometry in Synergy with other Techniques: Through the years mass spectrometers have evolved to be used not just on their own but used in tandem with a range of other analytic techniques such as Liquid Chromatography – Mass Spectrometry (LC-MS) in purity assessment and investigating rat urine, Gas Chromatography-Mass Spectrometry (GC-MS) for the detection and measurement of illicit drugs in biological fluids. It is LC-MS that has become the gold standard for detection and analyzation of substances. Gas chromatography works particularly well with mass spectrometry too, due to the face that the sample is already in its gaseous form at the interface. This system has been used by De Martinis and Barnes [9] in the detection of drugs in sweat using a quadrupole mass spectrometer which has been discussed earlier. The ability to identify metabolites in the biological fluids mentioned above can be very difficult and this is due to the fact that these metabolites are present in extremely low concentrations such as parts per mill ion (ppm) or even less in some situations. For many years Nuclear Magnetic Resonance (NMR) was used to identify these metabolites but in recent times it would appear that mass spectrometry has become the more popular method for detection of the metabolite. This may be due to the fact that MS is more sensitive than NMR resulting in less sample amount being required. 6. Advances in Mass Spectrometry Instruments and their Limitations: As mentioned briefly above it is very difficult to study large biomolecules such as proteins due to the fact that they are large polar molecules which are not volatile and as a result are difficult to convert to a gaseous state in order to undergo ionization. In recent years a solution to this problem has been accomplished with the introduction of Matrix- Assisted Laser Desorption Ionization (MALDI). MALDI is a laser based soft ionization method which relies on the sample being dissolved in a solution containing an excess of matrix such as sinapinic acid which has a chromophore that absorbs at the laser wavelength, the sample is placed in the path of high intensity protons causing a collision of the atoms with the sample resulting in ionization of the sample molecules causing them to be ejected from the matrix. One of the main advantages of MALDI-MS is that only a very tiny amount of sample is required (1 X 10-5 moles) [3]. This technique has proven to be one of the most successful ionization methods for mass spectrometry analysis of large molecules due to its soft ionization ability. This technique has been used in the drug-biomolecule complexes in order to investigate the interaction properties and sites of biomolecules with various drugs on the market today [10]. This method was also used by Zschorning et al. to investigate the extracts of human lipoproteins after treatment wi th cholesterol esterase’s [11]. This method although very popular suffers some drawbacks. There is a strong dependence on the sample preparation method and any mistake made during sample preparation or any contamination introduced into the matrix during the sample preparation renders the rest of the investigation pointless. Another draw back of this method is the short sample life although some research has been undertaken [12] with the use of liquid matrices in the belief that this may increase the sample life by making use of the self-healing properties of the sample through molecular diffusion. One obvious drawback that may occur is the fact that the sample may not be soluble and hence may not dissolve in the matrix. This problem may be overcome with the use of compression of a finely ground sample and analyte [13]. Another disadvantage which may become of detrimental in the future is the fact that MALDI is not easily compatible with LC-MS, this problem may have to be rectified id the popularity of MALDI is to c ontinue. Electrospray Ionization (ESI) has been described in detail under the methods of ionization section above and it can be seen that this young technique is proving to be very useful with LC-MS to investigate the a variety of molecules including proteins, DNA and synthetic polymers. The main problem with ESI-MS is that the mass spectra produced may contain many peaks of multiply charged ions which may cause confusion in the interpretation of spectra of some samples. The ESI instrument itself can also present with decreased sensitivity due to the presence of impurities such as salts and buffers, this is not the case with MALDI. Although both MALDI and ESI are both very effective methods of developing mass spectra for large molecules such as proteins, MALDI still remains the method of choice for most analyses. However, as discussed above the fact that MALDI is not very compatible with LC-MS may pave the way for a surge in popularity of the LC-MS friendly ESI. 7. The Future of Mass Spectrometry: Mass spectrometry has come along way since 1897 when Joseph J. Thompson used an early mass spectrometer to discover the electron and there is no reason why the mass spectrometer will continue to advance and evolve into the foreseeable future. The mass spectrometer is an extremely versatile analytical tool which can work in tandem and alongside other analytical methods such as chromatography seamlessly. The main areas in which mass spectrometers have been used for quantification of compounds are LC-MS and GC-MS using the various ionization methods respectively. LC-MS is the gold standard in quantitative bioanalyses and is used by the majority pharmaceutical companies. The other minority tend to use other techniques such as High Pressure Liquid Chromatography (HPLC) and UV as they deem LC-MS to be too expensive. An area of mass spectrometry to watch out for in the future is the use of ion-trap technology to perform LC-MS-MS to LC-MS [7]. This method already exists but reliable routine bioanalytical assays have not been produced as of yet. References: [1]  Ã‚   molecularstation.com/molecular-biology-images/506-molecular-biology-pictures/21-mass-spectrometer.html [2]  Ã‚   Daniel C. Harris: Quantitative Chemical Analysis, sixth edition (2003) published by W. H. Freeman and Company, New York. [3]  Ã‚   Donald L. Pavia, Gary M. Lampman, George S. Kriz and James R. Vyvyan: Introduction to Spectroscopy, fourth edition, published by Brooks/Cole, Cengage Learing. [4]  Ã‚   www.research.uky.edu/ukmsf/whatis.html [5]  Ã‚   Ionization Methods in Organic Mass Spectrometry [6]  Ã‚   Horning, E.C., Caroll, D.J., Dzidic, I., Haegele, K.D., Horning, M.G., and  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   Stillwell,R.N. (1974). Atmospheric pressure ionization (API) mass spectrometry. Solvent-mediated ionization of samples introduced in solution and in a liquid chromatograph effluent stream,   J. Chromatography. Sci, 12, (11), 725-729 [7]  Ã‚   RF Venn (Ed) (2000) Principles and practice of Bioanalysis Taylor and Francis. [8]  Ã‚   Ashcroft, A.E. (1997) Ionisation Methods in Organic Mass Spectrometry, Cambridge,   UK: The Royal Society of Chemistry. [9]  Ã‚   asms.org/whatisms/p1.html: The American Society of Mass Spectrometry [10]  Ã‚   Skelton, R., Dubols, F., Zenobl, R. Analytical Chemistry (2000), 72, 1707-1710 [11]  Ã‚   Zschornig, Markus Pietsch, Roesmarie SuB., Jurgen Schiller and Michael Gutschow. Cholesterol esterase action on human high density lipoproteins and inhibition studies: detection by MALDI-TOF MS.    [12]  Ã‚   Zenobi, R, Knochenmuss, R. Mass Spectrom, Rev. 1999, 17, 337-366.

LITTLE Surname Meaning and Origin

LITTLE Surname Meaning and Origin Little is a common  descriptive  surname often bestowed on someone who was of short or petite stature,  from the Middle English littel  and  Old English lytel, meaning little. In some cases the surname may have been used to denote the younger of two men of the same name.  KLEIN is the German variant and PETIT the French variant. Alternate Surname Spellings:  LITTLE, LITEL, LITTELL, LITTLE, LYTEL, LYTELL, LYTTELLE, LITTELLE, LYTLE, LYTTLE Surname Origin: English   Where in the World Do People with the LITTLE Surname Live? According to surname distribution data from Forebears, Little is a fairly common surname in most English-speaking countries, including the United States (where it ranks 276th), New Zealand (243rd), Australia (262nd), Scotland (256th), England (331st) and Canada (357th). Within England, Little is most common in the northern counties, especially Cumberland where it is the 11th most common last name. WorldNames PublicProfiler  indicates that in the United Kingdom,  Little is  most common in Cumbria County, England; Dumfries and Galloway, Scotland; and  Fermanagh, Northern Ireland. Within North America, Little is especially common in Nova Scotia, as well as the U.S. states of North Carolina and Mississippi.   Famous People with the LITTLE Last Name Lewis Henry Little - American  Civil War Confederate brigadier generalMalcolm Little - birth name of Malcolm X, African-American human rights activist  Arthur Dehon Little - American chemical engineerJean Little - Canadian writer Genealogy Resources for the Surname LITTLE Little Surname DNA ProjectThis DNA project was started in 2001 and has grown to include over 300 members with the surnames Little, Klein, Kline, or Cline interested in working collaboratively to combine genealogy research with DNA testing to sort out Little family lines. English Surname Meanings and OriginsUncover the meaning of your English last name with this guide to English surname meanings and origins. How to Research English  AncestryLearn how to research your English family tree with this guide to genealogical records in England and Wales, including birth, marriage, death, census, military and church records. Little Family Crest - Its Not What You ThinkContrary to what you may hear, there is no such thing as a Little  family crest or coat of arms for the Little surname.  Coats of arms are granted to individuals, not families, and may rightfully be used only by the uninterrupted male line descendants of the person to whom the coat of arms was originally granted.   LITTLE  Family Genealogy ForumSearch this popular genealogy forum for the Little surname to find others who might be researching your ancestors, or post your own Little genealogy query. FamilySearch - LITTLE GenealogyExplore over 2.7 million  historical records which mention individuals with the Little surname, as well as online Little family trees on this free website hosted by the Church of Jesus Christ of Latter-day Saints. GeneaNet - Little  RecordsGeneaNet includes archival records, family trees, and other resources for individuals with the Little surname, with a concentration on records and families from France and other European countries. DistantCousin.com - LITTLE  Genealogy Family HistoryExplore free databases and genealogy links for the last name Little. The Little  Genealogy and Family Tree PageBrowse family trees and links to genealogical and historical records for individuals with the last name Little  from the website of Genealogy Today. - References: Surname Meanings Origins Cottle, Basil.  Penguin Dictionary of Surnames. Baltimore, MD: Penguin Books, 1967. Dorward, David.  Scottish Surnames. Collins Celtic (Pocket edition), 1998. Fucilla, Joseph.  Our Italian Surnames. Genealogical Publishing Company, 2003. Hanks, Patrick and Flavia Hodges.  A Dictionary of Surnames. Oxford University Press, 1989. Hanks, Patrick.  Dictionary of American Family Names. Oxford University Press, 2003. Reaney, P.H.  A Dictionary of English Surnames. Oxford University Press, 1997. Smith, Elsdon C.  American Surnames. Genealogical Publishing Company, 1997. Back toGlossary of Surname Meanings Origins

Dell Boy Computers Case Study Example | Topics and Well Written Essays - 2000 words

Dell Boy Computers - Case Study Example (Whitehead, 1997) Dell Boy Computers relies on its brand name, the promise of support and its massive market presence to balance higher costs. As Dell Boy Computer Company is selling into an increasingly sophisticated and price-sensitive marketplace, it needs to do forward integration to market its profitable high-end computer products. To fortify its profit generating objective, Dell Boy goes into real estate development by creating apt settings for human activity that are in harmony with the environment and providing distribution services for its suppliers and customers. The top management of Dell Boy is restructuring the organization around common capabilities to achieve better strategic focus. The Company will renew profits and growth by focusing resources and management attention on three key areas: a.)Increase the volume and value of the market share in computer products through forward integration consisting of special warehouse services and an excellent service delivery platform; b.) Expand profit and revenue growth in personal computers by promoting aggressive and consistent marketing and promotional activities; and c.) focus on new business in the existing demand from the educational segment and in the small business and home personal computers segment.The company needs to be more selective about its property purchase as location is an important consideration for this project. The company can construct a big commercial lease building which can house its distribution operations and it can also be rented out to other commercial tenants.Through forward integration, Dell Boy Company will achieve important cost synergies, eliminate redundant management layers, and decrease other ancillary operating expenses including discretionary spending, which are expected to result in annual cost savings for the company. As Dell Boy Computer Company integrates forward into real estate, warehousing and distribution, the company needs to understand the benefits, and the development process this development entails. Property development for computer companies requires a clear perspective of public administration, physical planning, municipal regulation, market research, legal system, site appraisal, economic evaluation and assessment, financial contracts, contractual and bidding procedures, building design, construction designs, and marketing strategy aspects. The crucial costs of time, quality, and asset value are seriously considered. (Ratcliffe, et. al., 2003) The other leading computer companies such as Red Fox USA and Toshiba had relied on indirect distribution channels such as various retail stores and large shopping malls while Apple Computers, markets its products directly to the end users. For instance, Kwantinetz stated that Compaq's traditional sales and distribution technique covers a total of 90-day period for building, transporting, inventorying and setting the cost value of its manufactured goods to its existing indirect distribution channels. This very long lead time has added a tremendous 6 percent to Compaq's cost of business operations. To enable

Companies Conflict Resolution in Focus group Essay

Companies Conflict Resolution in Focus group - Essay Example External conflicts comprise of situations and issues seemingly created by others and which threaten personal and professional goals and desires of a person. It is often observed that poor communication among the workers and administrators lead to conflicting situations. â€Å"If resolution to a conflict is to end properly, it must begin properly – by negotiating a solvable problem. Therefore, the act of successful conflict resolution begins with the way the problem is examined† (Erickson). Thus, the best way to tackle workplace conflicts is to provide a neutral platform to the involved parties and thrash out the differences with a mediator with clear intention of solving it. The mediator is a person who facilitates easy communication between two warring groups or individuals with a well planned strategy. These facilitators are experts who specialize in human psychology with good listening power. They are assertive without being aggressive and confront the problems with an open mind which inspires confidence of the individuals involved. They provide an atmosphere that eases tension among the participants and promotes a proactive session where people can put forward their opinions without the threat of a backlash. These mediators often believe in forming focus groups of individuals followed by an interactive session among the group members with the facilitator subtly guiding the group towards resolution of the dispute or conflict and help generate as many different ideas and opinions as possible within a given time schedule. The mediators or moderators are helped by assistant moderator who takes notes and runs the recording of the discussion. Focus group is characterized by its homogeneity with relatively small number of people (normally from 8 to 12 persons) each of who are encouraged to voice their opinions. Main objective of the formation of the group is to go deep into the problem and